Granisetronum [INN-Latin]
Brand names,
Granisetronum [INN-Latin]
Analogs
Granisetronum [INN-Latin]
Brand Names Mixture
- Tarka (Trandolapril + Verapamil hydrochloride)
Granisetronum [INN-Latin]
Chemical_Formula
C18H24N4O
Granisetronum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic/granisetron.htm
Granisetronum [INN-Latin]
fda sheet
Granisetronum [INN-Latin]
msds (material safety sheet)
Granisetronum [INN-Latin]
Synthesis Reference
No information avaliable
Granisetronum [INN-Latin]
Molecular Weight
312.41 g/mol
Granisetronum [INN-Latin]
Melting Point
219 oC (HCl salt)
Granisetronum [INN-Latin]
H2O Solubility
No information avaliable
Granisetronum [INN-Latin]
State
Solid
Granisetronum [INN-Latin]
LogP
2.795
Granisetronum [INN-Latin]
Dosage Forms
Liquid; Tablet
Granisetronum [INN-Latin]
Indication
For the prevention of: nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin.
Granisetronum [INN-Latin]
Pharmacology
No information avaliable
Granisetronum [INN-Latin]
Absorption
Absorption of is rapid and complete, though oral bioavailability is reduced to about 60% as a result of first pass metabolism.
Granisetronum [INN-Latin]
side effects and Toxicity
LD50>2000 mg/kg (rat, oral)
Granisetronum [INN-Latin]
Patient Information
Granisetronum [INN-Latin]
Organisms Affected
Humans and other mammals